H₂
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hydroxyl radical scavenging
352 papers
Delivery-method distribution
hydrogen-rich water: 93
mixed routes: 71
inhalation: 66
in vitro: 41
injection / infusion: 34
not specified: 31
topical application: 9
animal model: 7
Inhalation of Hydrogen Attenuates Progression of Chronic Heart Failure via Suppression of Oxidative Stress and P53 Related to Apoptosis Pathway in Rats.
2018 ・ Front Physiol ・ PMID 30108516
inhalation
positive
animal study
[Research progress of hydrogen-rich saline for eye diseases].
2018 ・ Zhonghua Yan Ke Za Zhi ・ PMID 30107657
injection / infusion
not assessed
review
Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.
2018 ・ J Neuropathol Exp Neurol ・ PMID 30053086
inhalation
positive
animal study
The Role of Gaseous Molecules in Traumatic Brain Injury: An Updated Review.
2018 ・ Front Neurosci ・ PMID 29937711
not specified
not assessed
review
Administration of molecular hydrogen during pregnancy improves behavioral abnormalities of offspring in a maternal immune activation model.
2018 ・ Sci Rep ・ PMID 29907804
animal model
positive
animal study
Structural and lipid peroxidation effects of lead on rat hippocampus and its attenuation by hydrogen rich water.
2018 ・ J Chem Neuroanat ・ PMID 29694843
hydrogen-rich water
positive
animal study
Hydrogen-rich water improves cognitive impairment gender-dependently in APP/PS1 mice without affecting Aβ clearance.
2018 ・ Free Radic Res ・ PMID 29683360
hydrogen-rich water
mixed
animal study
Molecular hydrogen alleviates asphyxia-induced neuronal cyclooxygenase-2 expression in newborn pigs.
2018 ・ Acta Pharmacol Sin ・ PMID 29565041
inhalation
positive
animal study
Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.
2018 ・ J Cell Mol Med ・ PMID 29512923
hydrogen-rich water
positive
human observational study
Transplantation of High Hydrogen-Producing Microbiota Leads to Generation of Large Amounts of Colonic Hydrogen in Recipient Rats Fed High Amylose Maize Starch.
2018 ・ Nutrients ・ PMID 29382125
animal model
positive
animal study
Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen-rich saline in gerbil.
2018 ・ Neurosci Lett ・ PMID 29223865
injection / infusion
positive
animal study
Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
2018 ・ Curr Alzheimer Res ・ PMID 29110615
mixed routes
mixed
human randomized controlled trial
The transfer of hydrogen from inert gas to therapeutic gas.
2017 ・ Med Gas Res ・ PMID 29497488
not specified
not assessed
review
Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy.
2017 ・ Mol Clin Oncol ・ PMID 29142752
hydrogen-rich water
positive
human randomized controlled trial
Efficacy of inhaled HYdrogen on neurological outcome following BRain Ischemia During post-cardiac arrest care (HYBRID II trial): study protocol for a randomized controlled trial.
2017 ・ Trials ・ PMID 29058596
inhalation
not assessed
human randomized controlled trial
Hydrogen-rich pure water prevents cigarette smoke-induced pulmonary emphysema in SMP30 knockout mice.
2017 ・ Biochem Biophys Res Commun ・ PMID 28807355
hydrogen-rich water
positive
animal study
Molecular hydrogen in the treatment of acute and chronic neurological conditions: mechanisms of protection and routes of administration.
2017 ・ J Clin Biochem Nutr ・ PMID 28751802
mixed routes
not assessed
review
Influence of hydrogen-occluding-silica on migration and apoptosis in human esophageal cells.
2017 ・ Med Gas Res ・ PMID 28744359
in vitro
mixed
in vitro study
Hydrogen-rich medium protects mouse embryonic fibroblasts from oxidative stress by activating LKB1-AMPK-FoxO1 signal pathway.
2017 ・ Biochem Biophys Res Commun ・ PMID 28743498
in vitro
positive
in vitro study
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
2017 ・ J Stroke Cerebrovasc Dis ・ PMID 28669654
inhalation
positive
human randomized controlled trial
Hydrogen gas protects IP3Rs by reducing disulfide bridges in human keratinocytes under oxidative stress.
2017 ・ Sci Rep ・ PMID 28620198
in vitro
positive
in vitro study
Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
2017 ・ Neuroreport ・ PMID 28614179
inhalation
positive
animal study
Hydrogen generation by reaction of Si nanopowder with neutral water.
2017 ・ J Nanopart Res ・ PMID 28579914
in vitro
not assessed
other
Photoelectrochemical Degradation of Organic Compounds Coupled with Molecular Hydrogen Generation Using Electrochromic TiONanotube Arrays.
2017 ・ Environ Sci Technol ・ PMID 28445067
in vitro
not assessed
other
Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention.
2017 ・ Can J Physiol Pharmacol ・ PMID 28350967
injection / infusion
positive
animal study
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