H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Molecular hydrogen supplementation in mice ameliorates lipopolysaccharide-induced loss of interest.
2024 ・ PCN Rep ・ PMID 39171191
hydrogen-rich water
mixed
animal study
The Landscape of Smart Biomaterial-Based Hydrogen Therapy.
2024 ・ Adv Sci (Weinh) ・ PMID 39166484
mixed routes
not assessed
review
Hydrogen-rich water alleviates asthma airway inflammation by modulating tryptophan metabolism and activating aryl hydrocarbon receptor via gut microbiota regulation.
2024 ・ Free Radic Biol Med ・ PMID 39147072
hydrogen-rich water
positive
animal study
Combination of Hydrogen Inhalation and Hypothermic Temperature Control After Out-of-Hospital Cardiac Arrest: A Post hoc Analysis of the Efficacy of Inhaled Hydrogen on Neurologic Outcome Following Brain Ischemia During PostCardiac Arrest Care II Trial.
2024 ・ Crit Care Med ・ PMID 39133068
inhalation
mixed
human randomized controlled trial
Molecular Hydrogen for Outpatients with COVID-19 (Hydro-COVID): A Phase 3 Randomised, Triple-Blinded, Pragmatic, Placebo-Controlled, Multicentre Trial.
2024 ・ J Clin Med ・ PMID 39124575
hydrogen-rich water
null
human randomized controlled trial
A novel intervention of molecular hydrogen on the unbalance of the gut microbiome in opioid addiction: Experimental and human studies.
2024 ・ Biomed Pharmacother ・ PMID 39116782
mixed routes
positive
other
Effects of Molecular Hydrogen in the Pathophysiology and Management of Cardiovascular and Metabolic Diseases.
2024 ・ Rev Cardiovasc Med ・ PMID 39077646
mixed routes
not assessed
review
Realizing brain therapy with "smart medicine": mechanism and case report of molecular hydrogen inhalation for Parkinson's disease.
2024 ・ Med Gas Res ・ PMID 39073335
inhalation
positive
human case report
The Protective Role of Molecular Hydrogen in Ischemia/Reperfusion Injury.
2024 ・ Int J Mol Sci ・ PMID 39063126
mixed routes
not assessed
review
Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation.
2024 ・ Biomedicines ・ PMID 39062164
mixed routes
not assessed
review
Hydrogen-Rich Water (HRW) Reduces Fatty Acid-Induced Lipid Accumulation and Oxidative Stress Damage through Activating AMP-Activated Protein Kinase in HepG2 Cells.
2024 ・ Biomedicines ・ PMID 39062020
in vitro
positive
in vitro study
The Combination of Molecular Hydrogen and Heme Oxygenase 1 Effectively Inhibits Neuropathy Caused by Paclitaxel in Mice.
2024 ・ Antioxidants (Basel) ・ PMID 39061924
hydrogen-rich water
positive
animal study
Hinhalation therapy in patients with moderate COVID-19 (HCOVID): a prospective ascending-dose phase I clinical trial.
2024 ・ Antimicrob Agents Chemother ・ PMID 39016593
inhalation
positive
human case report
A Novel Antioxidant, Hydrogen-Rich Coral Calcium Alters Gut Microbiome and Bile Acid Synthesis to Improve Methionine-and-Choline-Deficient Diet-Induced Non-Alcoholic Fatty Liver Disease.
2024 ・ Antioxidants (Basel) ・ PMID 38929185
animal model
positive
animal study
An ethically guided preclinical device for phenotyping H2 production in laboratory rodents.
2024 ・ Animal Model Exp Med ・ PMID 38925626
not specified
not assessed
animal study
Light-Operated Transient Unilateral Adhesive Hydrogel for Comprehensive Prevention of Postoperative Adhesions.
2024 ・ Adv Sci (Weinh) ・ PMID 38924679
in vitro
positive
animal study
Molecular hydrogen promotes retinal vascular regeneration and attenuates neovascularization and neuroglial dysfunction in oxygen-induced retinopathy mice.
2024 ・ Biol Res ・ PMID 38915069
inhalation
positive
animal study
Mitigating radiation-induced brain injury via NLRP3/NLRC4/Caspase-1 pyroptosis pathway: Efficacy of memantine and hydrogen-rich water.
2024 ・ Biomed Pharmacother ・ PMID 38906028
hydrogen-rich water
positive
animal study
Can molecular hydrogen supplementation enhance physical performance in healthy adults? A systematic review and meta-analysis.
2024 ・ Front Nutr ・ PMID 38903627
mixed routes
mixed
meta-analysis
The GA and ABA signaling is required for hydrogen-mediated seed germination in wax gourd.
2024 ・ BMC Plant Biol ・ PMID 38872107
hydrogen-rich water
positive
other
Hydrogen-rich water alleviates constipation by attenuating oxidative stress through the sirtuin1/nuclear factor-erythroid-2-related factor 2/heme oxygenase-1 signaling pathway.
2024 ・ World J Gastroenterol ・ PMID 38855154
hydrogen-rich water
positive
animal study
Inhalation of hydrogen gas mitigates sevoflurane-induced neuronal apoptosis in the neonatal cortex and is associated with changes in protein phosphorylation.
2024 ・ J Neurochem ・ PMID 38849977
inhalation
positive
animal study
Potential role of molecular hydrogen therapy on oxidative stress and redox signaling in chronic kidney disease.
2024 ・ Biomed Pharmacother ・ PMID 38795643
mixed routes
not assessed
review
The Effect of 14-Day Consumption of Hydrogen-Rich Water Alleviates Fatigue but Does Not Ameliorate Dyspnea in Long-COVID Patients: A Pilot, Single-Blind, and Randomized, Controlled Trial.
2024 ・ Nutrients ・ PMID 38794767
hydrogen-rich water
mixed
human randomized controlled trial
[Rehabilitation program of post-COVID-19 syndrome with the use of nitric oxide and molecular hydrogen].
2024 ・ Ter Arkh ・ PMID 38713041
inhalation
positive
human randomized controlled trial
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