H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Direct Targets and Subsequent Pathways for Molecular Hydrogen to Exert Multiple Functions: Focusing on Interventions in Radical Reactions.
2021 ・ Curr Pharm Des ・ PMID 32767925
not specified
not assessed
review
Protective Effects of a Hydrogen-Rich Preservation Solution in a Canine Lung Transplantation Model.
2021 ・ Ann Thorac Surg ・ PMID 32649946
injection / infusion
positive
animal study
Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
2021 ・ Shock ・ PMID 32590694
inhalation
positive
animal study
Hydrogen and therapeutic gases for neonatal hypoxic-ischemic encephalopathy: potential neuroprotective adjuncts in translational research.
2021 ・ Pediatr Res ・ PMID 32505123
inhalation
not assessed
review
Inhaled Gases as Therapies for Post-Cardiac Arrest Syndrome: A Narrative Review of Recent Developments.
2020 ・ Front Med (Lausanne) ・ PMID 33585501
inhalation
not assessed
review
Magnesium Hydride-Mediated Sustainable Hydrogen Supply Prolongs the Vase Life of Cut Carnation Flowers via Hydrogen Sulfide.
2020 ・ Front Plant Sci ・ PMID 33362825
in vitro
positive
other
Molecular and Cellular Mechanisms Associated with Effects of Molecular Hydrogen in Cardiovascular and Central Nervous Systems.
2020 ・ Antioxidants (Basel) ・ PMID 33333951
mixed routes
not assessed
review
Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.
2020 ・ Front Immunol ・ PMID 33324415
hydrogen-rich water
positive
human observational study
Daily inhalation of hydrogen gas has a blood pressure-lowering effect in a rat model of hypertension.
2020 ・ Sci Rep ・ PMID 33244027
inhalation
positive
animal study
Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients.
2020 ・ Front Pharmacol ・ PMID 33178011
inhalation
not assessed
review
The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report.
2020 ・ Cent Nerv Syst Agents Med Chem ・ PMID 33167844
topical application
mixed
human case report
The Effects of Supersaturated Hydrogen-Rich Water Bathing on Biomarkers of Muscular Damage and Soreness Perception in Young Men Subjected to High-Intensity Eccentric Exercise.
2020 ・ J Sports Med (Hindawi Publ Corp) ・ PMID 33123594
hydrogen bath
positive
human randomized controlled trial
Molecular hydrogen alleviates brain injury and cognitive impairment in a chronic sequelae model of murine polymicrobial sepsis.
2020 ・ Exp Brain Res ・ PMID 33052428
inhalation
positive
animal study
Hydrogen gas inhalation alleviates oxidative stress in patients with post-cardiac arrest syndrome.
2020 ・ J Clin Biochem Nutr ・ PMID 33041520
inhalation
mixed
human case report
Inhaled Hor CODo Not Augment the Neuroprotective Effect of Therapeutic Hypothermia in a Severe Neonatal Hypoxic-Ischemic Encephalopathy Piglet Model.
2020 ・ Int J Mol Sci ・ PMID 32948011
inhalation
null
animal study
Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.
2020 ・ Brain Res ・ PMID 32919984
hydrogen-rich water
positive
animal study
Hydrogenases and the Role of Molecular Hydrogen in Plants.
2020 ・ Plants (Basel) ・ PMID 32887396
not specified
not assessed
review
COVID-19 and molecular hydrogen inhalation.
2020 ・ Ther Adv Respir Dis ・ PMID 32865158
inhalation
not assessed
letter
Prospects of molecular hydrogen in perioperative neuroprotection from basic research to clinical application.
2020 ・ Curr Opin Anaesthesiol ・ PMID 32826628
mixed routes
not assessed
review
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
2020 ・ Brain Res ・ PMID 32814064
inhalation
positive
animal study
Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model.
2020 ・ Shock ・ PMID 32804466
inhalation
positive
animal study
Molecular hydrogen: A potential radioprotective agent.
2020 ・ Biomed Pharmacother ・ PMID 32763820
mixed routes
not assessed
review
Hydrogen gas inhalation improves delayed brain injury by alleviating early brain injury after experimental subarachnoid hemorrhage.
2020 ・ Sci Rep ・ PMID 32704088
inhalation
positive
animal study
Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial.
2020 ・ Sci Rep ・ PMID 32699287
hydrogen-rich water
mixed
human randomized controlled trial
An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
2020 ・ Oxid Med Cell Longev ・ PMID 32655773
topical application
positive
animal study
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