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COVID-19 and molecular hydrogen inhalation.

COVID-19と分子状水素吸入に関する考察

letter inhalation not assessed

Abstract

This letter discusses the potential relevance of molecular hydrogen (H2) inhalation in the context of COVID-19. H2 is recognized for its antioxidant and anti-inflammatory properties, and the author explores whether these characteristics may be relevant to respiratory complications and oxidative stress associated with COVID-19 infection. No detailed abstract is available for this publication, but the correspondence addresses the scientific rationale for considering H2 inhalation in this disease context.

Mechanism

H2 may reduce oxidative stress and inflammatory responses associated with COVID-19 through its established antioxidant and anti-inflammatory properties.

Bibliographic

Authors
Ostojic SM
Journal
Ther Adv Respir Dis
Year
2020
PMID
32865158
DOI
10.1177/1753466620951051
PMC
PMC7459175

Tags

Disease:COVID-19 Delivery:吸入投与 Mechanism:抗酸化酵素 炎症抑制 酸化ストレス 活性酸素種

Delivery context

For inhalation applications of molecular hydrogen, the lower flammability limit (LFL) deserves careful handling. The classical 4% figure applies to closed-system mixtures; the practical inhalation-environment threshold is 10%. Even pure-hydrogen output (the UFL 75% paradox) passes through the flammable range at the air–gas boundary. High-concentration (66% / 100%) inhalers are documented in the Japanese Consumer Affairs Agency accident-information database and are not recommended.

Safety notes

For inhalation applications of molecular hydrogen, the lower flammability limit (LFL) deserves careful handling. The classical 4% figure applies to closed-system mixtures; the practical inhalation-environment threshold is 10%. Even pure-hydrogen output (the UFL 75% paradox) passes through the flammable range at the air–gas boundary. High-concentration (66% / 100%) inhalers are documented in the Japanese Consumer Affairs Agency accident-information database and are not recommended.

See also:

Other papers on the same disease / condition

Cite as: H2 Papers — PMID 32865158. https://h2-papers.org/en/papers/32865158
Source: PubMed PMID 32865158