H₂
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immune modulation
180 papers
Delivery-method distribution
hydrogen-rich water: 61
mixed routes: 33
inhalation: 29
not specified: 20
in vitro: 17
injection / infusion: 10
topical application: 4
animal model: 4
hydrogen bath: 2
APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis.
2023 ・ Int J Mol Sci ・ PMID 37511084
animal model
positive
animal study
Inhaled molecular hydrogen reduces hippocampal neuroinflammation, glial reactivity and ameliorates memory impairment during systemic inflammation.
2023 ・ Brain Behav Immun Health ・ PMID 37449286
inhalation
positive
animal study
Hydrogen-rich water treatment targets RT1-Db1 and RT1-Bb to alleviate premature ovarian failure in rats.
2023 ・ PeerJ ・ PMID 37397014
hydrogen-rich water
positive
animal study
Effect and mechanism of hydrogen-rich bath on mice with imiquimod-induced psoriasis.
2023 ・ Exp Dermatol ・ PMID 37391861
hydrogen bath
positive
animal study
Hydrogen Attenuates Inflammation by Inducing Early M2 Macrophage Polarization in Skin Wound Healing.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37375833
inhalation
positive
animal study
Mast Cells as a Potential Target of Molecular Hydrogen in Regulating the Local Tissue Microenvironment.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37375765
not specified
not assessed
review
Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study.
2023 ・ Antioxidants (Basel) ・ PMID 37371975
hydrogen-rich water
positive
human randomized controlled trial
Trend of research on the medical use of molecular hydrogen: a bibliometric analysis.
2023 ・ Med Gas Res ・ PMID 37077121
mixed routes
not assessed
review
Molecular Hydrogen: From Molecular Effects to Stem Cells Management and Tissue Regeneration.
2023 ・ Antioxidants (Basel) ・ PMID 36978884
mixed routes
not assessed
review
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition.
2023 ・ Inflamm Regen ・ PMID 36973725
inhalation
positive
animal study
Novel therapeutic approaches based on the pathological role of gut dysbiosis on the link between nonalcoholic fatty liver disease and insulin resistance.
2023 ・ Eur Rev Med Pharmacol Sci ・ PMID 36930488
hydrogen-rich water
not assessed
review
Molecular Hydrogen Confers Resistance to Rice Stripe Virus.
2023 ・ Microbiol Spectr ・ PMID 36840556
in vitro
positive
other
Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
2023 ・ Brain Res Bull ・ PMID 36516898
mixed routes
positive
human observational study
Ameliorating Role of Hydrogen-Rich Water Against NSAID-Induced Enteropathy via Reduction of ROS and Production of Short-Chain Fatty Acids.
2023 ・ Dig Dis Sci ・ PMID 36478314
hydrogen-rich water
positive
animal study
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
2023 ・ CNS Neurosci Ther ・ PMID 36468415
mixed routes
positive
animal study
Effects of hydrogen rich water and pure water on periodontal inflammatory factor level, oxidative stress level and oral flora: a systematic review and meta-analysis.
2022 ・ Ann Transl Med ・ PMID 36388830
hydrogen-rich water
positive
meta-analysis
Molecular hydrogen has a positive impact on pregnancy maintenance through enhancement of mitochondrial function and immunomodulatory effects on T cells.
2022 ・ Life Sci ・ PMID 36115583
mixed routes
positive
human observational study
Malproduction of endogenous hydrogen gas in COVID-19.
2022 ・ Front Cell Infect Microbiol ・ PMID 35967841
not specified
not assessed
review
Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial.
2022 ・ Health Psychol Res ・ PMID 35774917
hydrogen-rich water
mixed
human randomized controlled trial
Hydrogen Gas Inhalation Regressed Coronary Artery Aneurysm in Kawasaki Disease-Case Report and Article Review.
2022 ・ Front Cardiovasc Med ・ PMID 35647081
inhalation
positive
human case report
Different effects of hydrogen-rich water intake and hydrogen gas inhalation on gut microbiome and plasma metabolites of rats in health status.
2022 ・ Sci Rep ・ PMID 35508571
mixed routes
mixed
animal study
Long-term and daily use of molecular hydrogen induces reprogramming of liver metabolism in rats by modulating NADP/NADPH redox pathways.
2022 ・ Sci Rep ・ PMID 35273249
mixed routes
positive
animal study
H2 Inhibits the Formation of Neutrophil Extracellular Traps.
2022 ・ JACC Basic Transl Sci ・ PMID 35257042
mixed routes
positive
in vitro study
Nano-bubble hydrogen water: An effective therapeutic agent against inflammation related disease caused by viral infection in zebrafish model.
2022 ・ Virol Sin ・ PMID 35249853
hydrogen-rich water
positive
animal study
Molecular hydrogen alleviates lung injury after traumatic brain injury: Pyroptosis and apoptosis.
2022 ・ Eur J Pharmacol ・ PMID 34883075
inhalation
positive
animal study
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