H₂
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oxidative stress
899 papers
Delivery-method distribution
hydrogen-rich water: 313
inhalation: 153
mixed routes: 150
in vitro: 103
injection / infusion: 72
not specified: 66
topical application: 19
animal model: 15
hydrogen bath: 8
Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
2016 ・ Free Radic Biol Med ・ PMID 27789293
mixed routes
positive
animal study
The Clinical Application of Hydrogen as a Medical Treatment.
2016 ・ Acta Med Okayama ・ PMID 27777424
mixed routes
not assessed
review
Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice.
2016 ・ Oxid Med Cell Longev ・ PMID 27774116
animal model
positive
animal study
Hydrogen-rich Water Exerting a Protective Effect on Ovarian Reserve Function in a Mouse Model of Immune Premature Ovarian Failure Induced by Zona Pellucida 3.
2016 ・ Chin Med J (Engl) ・ PMID 27647193
hydrogen-rich water
positive
animal study
Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals.
2016 ・ Physiol Res ・ PMID 27643933
mixed routes
not assessed
review
The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
2016 ・ Inflammation ・ PMID 27624060
in vitro
positive
in vitro study
Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis.
2016 ・ Med Sci Monit ・ PMID 27606690
injection / infusion
not assessed
other
Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
2016 ・ Sci Rep ・ PMID 27558955
mixed routes
positive
in vitro study
Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
2016 ・ Circ J ・ PMID 27477846
in vitro
positive
in vitro study
Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.
2016 ・ Oxid Med Cell Longev ・ PMID 27413421
mixed routes
not assessed
review
Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
2016 ・ Neurochem Res ・ PMID 27386874
injection / infusion
positive
animal study
Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model.
2016 ・ Exp Ther Med ・ PMID 27284352
inhalation
positive
animal study
Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
2016 ・ J Neuroimmunol ・ PMID 27138092
hydrogen-rich water
positive
animal study
Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.
2016 ・ PLoS One ・ PMID 27115738
mixed routes
positive
in vitro study
Effects of hydrogen-rich water on depressive-like behavior in mice.
2016 ・ Sci Rep ・ PMID 27026206
hydrogen-rich water
positive
animal study
Suppression of ERK phosphorylation through oxidative stress is involved in the mechanism underlying sevoflurane-induced toxicity in the developing brain.
2016 ・ Sci Rep ・ PMID 26905012
inhalation
positive
animal study
Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin-Radixin-Moesin Signaling Pathways.
2016 ・ Chin J Physiol ・ PMID 26875562
mixed routes
positive
in vitro study
Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
2016 ・ Shock ・ PMID 26849632
inhalation
positive
animal study
Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
2016 ・ Pediatr Pulmonol ・ PMID 26845501
mixed routes
positive
animal study
Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
2016 ・ Brain Res ・ PMID 26826009
injection / infusion
positive
animal study
Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer.
2016 ・ Biochem Pharmacol ・ PMID 26774456
hydrogen-rich water
positive
animal study
Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
2016 ・ Sci Rep ・ PMID 26739257
in vitro
positive
in vitro study
Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia.
2016 ・ Free Radic Biol Med ・ PMID 26709014
hydrogen-rich water
positive
animal study
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
2016 ・ Brain Res ・ PMID 26705611
inhalation
positive
animal study
MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
2016 ・ FEBS J ・ PMID 26683671
mixed routes
positive
animal study
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