reactive oxygen species

774 papers

Research evidence summary

Q: Does molecular hydrogen help with reactive oxygen species?

A: Of 774 peer-reviewed papers, 515 reported a positive effect (the most common), 50 limited/mixed, 5 negative, 203 not assessed. Study mix: 94 human (50 RCT), 456 animal/basic, 153 meta-analysis or synthesis. The most studied delivery route is hydrogen-rich water. The above aggregates published research and does not constitute a clinically established conclusion. See the individual paper pages for details and Safety notes for inhalation safety. (last updated 2026-05-15)

Evidence breakdown
Human94of which RCT50
Animal/basic456Synthesis/meta153
Reported effectpositive 515 ・ limited/mixed 50 ・ negative 5 ・ not assessed 203

Read the safety notes →

Delivery-method distribution

hydrogen-rich water: 224 in vitro: 135 inhalation: 133 mixed routes: 118 not specified: 75 injection / infusion: 58 topical application: 14 animal model: 12 hydrogen bath: 5