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wound healing
35 papers
Delivery-method distribution
topical application: 14
in vitro: 8
inhalation: 4
hydrogen-rich water: 4
mixed routes: 2
hydrogen bath: 2
not specified: 1
Molecular hydrogen triggers TRPC4-TRPC4AP-dependent reversible calcium transients via extracellular influx.
2026 ・ Theranostics ・ PMID 41799190
inhalation
positive
in vitro study
Exploratory Evaluation of Hydrogen-Rich Water Therapy for Keloid Management: A Double-Blinded Randomized Pilot Trial.
2026 ・ Aesthetic Plast Surg ・ PMID 41545661
hydrogen-rich water
positive
human randomized controlled trial
Sequential hydrogen-release implant for promoting the soft tissue integration through immunomodulatory and pro-remodeling coupling.
2026 ・ Bioact Mater ・ PMID 41334374
in vitro
positive
in vitro study
Postharvest preservation of chestnuts: Combined application of hydrogen-rich water and a carboxymethyl chitosan/sodium alginate composite coating.
2026 ・ Int J Biol Macromol ・ PMID 41314584
hydrogen-rich water
positive
other
Topically Applied Molecular Hydrogen Normalizes Skin Parameters Associated with Oxidative Stress: A Pilot Study.
2025 ・ Antioxidants (Basel) ・ PMID 40563361
topical application
positive
human case report
Coaxial Fibrous Dressing Enabling Sequential NO/HRelease for Temporally Programmed Antibacterial and Healing-Promoting Functions in Infected Diabetic Wound Treatment.
2025 ・ ACS Appl Mater Interfaces ・ PMID 40504663
topical application
positive
animal study
Local Visible-Photocatalytic Production of Hydrogen and Warm Heat for Combination Treatment of Pressure Ulcer.
2025 ・ Adv Sci (Weinh) ・ PMID 40491331
topical application
positive
animal study
Synergistic Antioxidant Effects of Molecular Hydrogen and Cold Atmospheric Plasma in Enhancing Mesenchymal Stem Cell Therapy.
2024 ・ Antioxidants (Basel) ・ PMID 39765910
mixed routes
not assessed
review
Hydrogen-releasing magnesium hydrogel mitigates post laminectomy epidural fibrosis through inhibition of neutrophil extracellular traps.
2024 ・ Acta Biomater ・ PMID 39260811
in vitro
positive
animal study
Light-Operated Transient Unilateral Adhesive Hydrogel for Comprehensive Prevention of Postoperative Adhesions.
2024 ・ Adv Sci (Weinh) ・ PMID 38924679
in vitro
positive
animal study
Combined use of hydrogen-rich water and enzyme-digested edible bird's nest improves PMA/LPS-impaired wound healing in human inflammatory gingival tissue equivalents.
2024 ・ Hum Cell ・ PMID 38679666
in vitro
positive
in vitro study
Solid-state atomic hydrogen as a broad-spectrum RONS scavenger for accelerated diabetic wound healing.
2024 ・ Natl Sci Rev ・ PMID 38213516
topical application
positive
animal study
Hydrogen Attenuates Inflammation by Inducing Early M2 Macrophage Polarization in Skin Wound Healing.
2023 ・ Pharmaceuticals (Basel) ・ PMID 37375833
inhalation
positive
animal study
Mast Cells in Regeneration of the Skin in Burn Wound with Special Emphasis on Molecular Hydrogen Effect.
2023 ・ Pharmaceuticals (Basel) ・ PMID 36986447
mixed routes
positive
animal study
Alginate-Based Biomaterials in Tissue Engineering and Regenerative Medicine.
2023 ・ Mar Drugs ・ PMID 36976238
not specified
not assessed
review
Molecular hydrogen promotes wound healing by inducing early epidermal stem cell proliferation and extracellular matrix deposition.
2023 ・ Inflamm Regen ・ PMID 36973725
inhalation
positive
animal study
Two-Dimensional MgSi Nanosheet-Enabled Sustained Hydrogen Generation for Improved Repair and Regeneration of Deeply Burned Skin.
2023 ・ Adv Healthc Mater ・ PMID 36546774
topical application
positive
in vitro study
Hydrogen-producing Photocatalyst at Sunscreen for Athletes in Preventing and Healing Muscle-nerve-skin Injuries.
2023 ・ Curr Top Med Chem ・ PMID 36529921
topical application
not assessed
review
Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing.
2022 ・ Nat Commun ・ PMID 36167814
topical application
positive
animal study
Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.
2022 ・ Int J Mol Sci ・ PMID 36077171
topical application
positive
animal study
Symbiotic Algae-Bacteria Dressing for Producing Hydrogen to Accelerate Diabetic Wound Healing.
2022 ・ Nano Lett ・ PMID 34928162
topical application
positive
in vitro study
The Therapeutic Effects of Oral Intake of Hydrogen Rich Water on Cutaneous Wound Healing in Dogs.
2021 ・ Vet Sci ・ PMID 34822637
hydrogen-rich water
positive
animal study
Hydrotherapy with hydrogen-rich water compared with RICE protocol following acute ankle sprain in professional athletes: a randomized non-inferiority pilot trial.
2021 ・ Res Sports Med ・ PMID 33356580
hydrogen bath
null
human randomized controlled trial
Antioxidant Activity of Hydrogen Water Mask Pack Composed of Gel-Type Emulsion and Hydrogen Generation Powder.
2020 ・ Int J Mol Sci ・ PMID 33419292
topical application
positive
human observational study
An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
2020 ・ Oxid Med Cell Longev ・ PMID 32655773
topical application
positive
animal study
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