H₂
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antioxidant enzymes
423 papers
Delivery-method distribution
hydrogen-rich water: 179
in vitro: 65
inhalation: 48
mixed routes: 47
injection / infusion: 36
not specified: 30
animal model: 8
topical application: 7
hydrogen bath: 3
Hydrogen-rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum.
2017 ・ Environ Microbiol ・ PMID 27554678
in vitro
positive
in vitro study
Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.
2017 ・ Redox Rep ・ PMID 26866650
hydrogen-rich water
positive
animal study
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29920028
inhalation
positive
animal study
Molecular hydrogen: a therapeutic antioxidant and beyond.
2016 ・ Med Gas Res ・ PMID 28217294
not specified
not assessed
review
Should hydrogen therapy be included in a musculoskeletal medicine routine?
2016 ・ F1000Res ・ PMID 28003879
mixed routes
not assessed
review
Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease.
2016 ・ Med Gas Res ・ PMID 27867488
hydrogen-rich water
positive
human case report
Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
2016 ・ Am J Transl Res ・ PMID 27830032
in vitro
positive
animal study
Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice.
2016 ・ Oxid Med Cell Longev ・ PMID 27774116
animal model
positive
animal study
Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals.
2016 ・ Physiol Res ・ PMID 27643933
mixed routes
not assessed
review
The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
2016 ・ Inflammation ・ PMID 27624060
in vitro
positive
in vitro study
Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis.
2016 ・ Med Sci Monit ・ PMID 27606690
injection / infusion
not assessed
other
Molecular Hydrogen Alleviates Cellular Senescence in Endothelial Cells.
2016 ・ Circ J ・ PMID 27477846
in vitro
positive
in vitro study
Combination therapy of molecular hydrogen and hyperoxia improves survival rate and organ damage in a zymosan-induced generalized inflammation model.
2016 ・ Exp Ther Med ・ PMID 27284352
inhalation
positive
animal study
Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
2016 ・ Pediatr Pulmonol ・ PMID 26845501
mixed routes
positive
animal study
Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators.
2016 ・ Sci Rep ・ PMID 26739257
in vitro
positive
in vitro study
Is melanin a source of bioactive molecular hydrogen?
2016 ・ Pharmacol Res ・ PMID 26657415
not specified
not assessed
letter
Hydrogen-rich water-alleviated ultraviolet-B-triggered oxidative damage is partially associated with the manipulation of the metabolism of (iso)flavonoids and antioxidant defence in Medicago sativa.
2015 ・ Funct Plant Biol ・ PMID 32480752
hydrogen-rich water
positive
other
[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].
2015 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 27132459
injection / infusion
positive
animal study
Drinking Hydrogen-Rich Water Has Additive Effects on Non-Surgical Periodontal Treatment of Improving Periodontitis: A Pilot Study.
2015 ・ Antioxidants (Basel) ・ PMID 26783840
hydrogen-rich water
positive
human observational study
Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
2015 ・ Invest Ophthalmol Vis Sci ・ PMID 26720481
injection / infusion
positive
animal study
[Initiation, development and potential of hydrogen medicine: Toward therapeutic and preventive applications of molecular hydrogen against a variety of diseases].
2015 ・ Seikagaku ・ PMID 26571560
mixed routes
not assessed
review
Hydrogen-rich saline may be an effective and specific novel treatment for osteoradionecrosis of the jaw.
2015 ・ Ther Clin Risk Manag ・ PMID 26508867
injection / infusion
not assessed
letter
Intravenous infusion of H2-saline suppresses oxidative stress and elevates antioxidant potential in Thoroughbred horses after racing exercise.
2015 ・ Sci Rep ・ PMID 26493164
injection / infusion
positive
animal study
Cadmium-Induced Hydrogen Accumulation Is Involved in Cadmium Tolerance in Brassica campestris by Reestablishment of Reduced Glutathione Homeostasis.
2015 ・ PLoS One ・ PMID 26445361
hydrogen-rich water
positive
in vitro study
Hydrogen-rich water attenuates amyloid β-induced cytotoxicity through upregulation of Sirt1-FoxO3a by stimulation of AMP-activated protein kinase in SK-N-MC cells.
2015 ・ Chem Biol Interact ・ PMID 26271894
in vitro
positive
in vitro study
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