H₂
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anti-inflammatory
743 papers
Delivery-method distribution
hydrogen-rich water: 254
inhalation: 140
mixed routes: 129
not specified: 61
in vitro: 61
injection / infusion: 60
topical application: 17
animal model: 15
hydrogen bath: 6
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
2017 ・ Neuropharmacology ・ PMID 28359771
injection / infusion
positive
animal study
Molecular hydrogen potentiates beneficial anti-infarct effect of hypoxic postconditioning in isolated rat hearts: a novel cardioprotective intervention.
2017 ・ Can J Physiol Pharmacol ・ PMID 28350967
injection / infusion
positive
animal study
The Effects of Hydrogen Gas Inhalation on Adverse Left Ventricular Remodeling After Percutaneous Coronary Intervention for ST-Elevated Myocardial Infarction - First Pilot Study in Humans.
2017 ・ Circ J ・ PMID 28321000
inhalation
mixed
human observational study
Hydrogen-rich water protects against inflammatory bowel disease in mice by inhibiting endoplasmic reticulum stress and promoting heme oxygenase-1 expression.
2017 ・ World J Gastroenterol ・ PMID 28293084
hydrogen-rich water
positive
animal study
Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release.
2017 ・ Shock ・ PMID 28234792
inhalation
positive
animal study
Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
2017 ・ Mol Med Rep ・ PMID 28098910
injection / infusion
positive
animal study
Preventive Effects of Drinking Hydrogen-Rich Water on Gingival Oxidative Stress and Alveolar Bone Resorption in Rats Fed a High-Fat Diet.
2017 ・ Nutrients ・ PMID 28098768
hydrogen-rich water
positive
animal study
Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
2017 ・ Shock ・ PMID 27918369
hydrogen-rich water
positive
animal study
Molecular Hydrogen as a Neuroprotective Agent.
2017 ・ Curr Neuropharmacol ・ PMID 27281176
mixed routes
not assessed
review
Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.
2017 ・ Redox Rep ・ PMID 26866650
hydrogen-rich water
positive
animal study
[Effects of hydrogen-rich water on the expression of aquaporin 1 in the cerebral cortex of rat with traumatic brain injury].
2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29923387
injection / infusion
positive
animal study
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
2016 ・ Zhonghua Wei Zhong Bing Ji Jiu Yi Xue ・ PMID 29920028
inhalation
positive
animal study
Molecular hydrogen stimulates the gene expression of transcriptional coactivator PGC-1α to enhance fatty acid metabolism.
2016 ・ NPJ Aging Mech Dis ・ PMID 28721265
hydrogen-rich water
positive
animal study
Molecular hydrogen: a therapeutic antioxidant and beyond.
2016 ・ Med Gas Res ・ PMID 28217294
not specified
not assessed
review
Molecular hydrogen affords neuroprotection in a translational piglet model of hypoxic-ischemic encephalopathy.
2016 ・ J Physiol Pharmacol ・ PMID 28011948
inhalation
positive
animal study
Should hydrogen therapy be included in a musculoskeletal medicine routine?
2016 ・ F1000Res ・ PMID 28003879
mixed routes
not assessed
review
Successful treatment with hydrogen rich water in a case of chronic graft-versus-host-disease.
2016 ・ Med Gas Res ・ PMID 27867488
hydrogen-rich water
positive
human case report
Molecular hydrogen decelerates rheumatoid arthritis progression through inhibition of oxidative stress.
2016 ・ Am J Transl Res ・ PMID 27830032
in vitro
positive
animal study
Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
2016 ・ Free Radic Biol Med ・ PMID 27789293
mixed routes
positive
animal study
Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice.
2016 ・ Oxid Med Cell Longev ・ PMID 27774116
animal model
positive
animal study
Preventive and therapeutic application of molecular hydrogen in situations with excessive production of free radicals.
2016 ・ Physiol Res ・ PMID 27643933
mixed routes
not assessed
review
The Effects of Molecular Hydrogen and Suberoylanilide Hydroxamic Acid on Paraquat-Induced Production of Reactive Oxygen Species and TNF-α in Macrophages.
2016 ・ Inflammation ・ PMID 27624060
in vitro
positive
in vitro study
Hydrogen-Rich Saline as an Innovative Therapy for Cataract: A Hypothesis.
2016 ・ Med Sci Monit ・ PMID 27606690
injection / infusion
not assessed
other
Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
2016 ・ Sci Rep ・ PMID 27558955
mixed routes
positive
in vitro study
Hydrogen Metabolism in Helicobacter pylori Plays a Role in Gastric Carcinogenesis through Facilitating CagA Translocation.
2016 ・ mBio ・ PMID 27531909
in vitro
not assessed
other
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