depression / anxiety

34 papers

• Molecular Hydrogen Reverses Nociplastic Pain and Depressive-like Behaviors via Region- and Sex-Dependent Central Mechanisms.
  2026 ・ Int J Mol Sci ・ PMID 41977237
  hydrogen-rich water positive animal study
• Modulating NLRP3 Inflammasome Activity and Enhancing Cortical Synaptic Plasticity: Nanoparticulate Hydrogen's Role in Relief of Post-traumatic Anxiety-like Behaviors in Rats.
  2025 ・ Mol Neurobiol ・ PMID 41261203
  injection / infusion positive animal study
• Preventing Cisplatin-Induced Neuropathy and Related Emotional Disorders with the Coadministration of Duloxetine and Hydrogen-Rich Water in Male and Female Mice.
  2025 ・ Antioxidants (Basel) ・ PMID 40867900
  mixed routes positive animal study
• Role of Cholesterol in Mediating Interaction of Antidepressant Amitriptyline with Phospholipid Membranes.
  2025 ・ Langmuir ・ PMID 40492616
  in vitro not assessed in vitro study
• Hydrogen restores central tryptophan and metabolite levels and maintains mitochondrial homeostasis to protect rats from chronic mild unpredictable stress damage.
  2025 ・ Neurochem Int ・ PMID 39653185
  inhalation positive animal study
• Molecular hydrogen inhibits neuroinflammation and ameliorates depressive-like behaviors and short-term cognitive impairment in senescence-accelerated mouse prone 8 mice.
  2025 ・ Behav Brain Res ・ PMID 39522774
  hydrogen-rich water positive animal study
• Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer's disease: targeting oxidative stress, inflammation, and the gut-brain axis.
  2024 ・ Front Aging Neurosci ・ PMID 39839307
  hydrogen-rich water positive animal study
• Inhalation of H/O(66.7 %/33.3 %) mitigates depression-like behaviors in diabetes mellitus complicated with depression mice via suppressing inflammation and preventing hippocampal damage.
  2024 ・ Biomed Pharmacother ・ PMID 39405908
  inhalation positive animal study
• Molecular hydrogen supplementation in mice ameliorates lipopolysaccharide-induced loss of interest.
  2024 ・ PCN Rep ・ PMID 39171191
  hydrogen-rich water mixed animal study
• A novel intervention of molecular hydrogen on the unbalance of the gut microbiome in opioid addiction: Experimental and human studies.
  2024 ・ Biomed Pharmacother ・ PMID 39116782
  mixed routes positive other
• The Effect of 14-Day Consumption of Hydrogen-Rich Water Alleviates Fatigue but Does Not Ameliorate Dyspnea in Long-COVID Patients: A Pilot, Single-Blind, and Randomized, Controlled Trial.
  2024 ・ Nutrients ・ PMID 38794767
  hydrogen-rich water mixed human randomized controlled trial
• The effect of hydrogen-rich water consumption on premenstrual symptoms and quality of life: a randomized controlled trial.
  2024 ・ BMC Womens Health ・ PMID 38532373
  hydrogen-rich water positive human randomized controlled trial
• Decoupling the mutual promotion of inflammation and oxidative stress mitigates cognitive decline and depression-like behavior in rmTBI mice by promoting myelin renewal and neuronal survival.
  2024 ・ Biomed Pharmacother ・ PMID 38479178
  hydrogen-rich water positive animal study
• A Novel Therapy for Cisplatin-Induced Allodynia and Dysfunctional and Emotional Impairments in Male and Female Mice.
  2023 ・ Antioxidants (Basel) ・ PMID 38136183
  hydrogen-rich water positive animal study
• Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans.
  2023 ・ Arch Med Sci ・ PMID 37560746
  hydrogen-rich water positive human observational study
• Transcriptomic and metabolomic studies on the protective effect of molecular hydrogen against nuclear electromagnetic pulse-induced brain damage.
  2023 ・ Front Public Health ・ PMID 36817910
  hydrogen-rich water positive animal study
• Molecular Hydrogen: an Emerging Therapeutic Medical Gas for Brain Disorders.
  2023 ・ Mol Neurobiol ・ PMID 36567361
  mixed routes not assessed review
• Effects of molecular hydrogen intervention on the gut microbiome in methamphetamine abusers with mental disorder.
  2023 ・ Brain Res Bull ・ PMID 36516898
  mixed routes positive human observational study
• New Treatment for the Cognitive and Emotional Deficits Linked with Paclitaxel-Induced Peripheral Neuropathy in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36552595
  hydrogen-rich water positive animal study
• Treatment with Hydrogen-Rich Water Improves the Nociceptive and Anxio-Depressive-like Behaviors Associated with Chronic Inflammatory Pain in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36358525
  injection / infusion positive animal study
• Hydrogen-Rich Water as a Novel Therapeutic Strategy for the Affective Disorders Linked with Chronic Neuropathic Pain in Mice.
  2022 ・ Antioxidants (Basel) ・ PMID 36139900
  hydrogen-rich water positive animal study
• Post-COVID-19 fatigue: A systematic review.
  2022 ・ Front Psychiatry ・ PMID 36032234
  inhalation positive review
• Effects of hydrogen water and psychological treatment in a sample of women with panic disorder: a randomized and controlled clinical trial.
  2022 ・ Health Psychol Res ・ PMID 35774917
  hydrogen-rich water mixed human randomized controlled trial
• The Role of Hyperthermia in Methamphetamine-Induced Depression-Like Behaviors: Protective Effects of Coral Calcium Hydride.
  2021 ・ Front Mol Neurosci ・ PMID 35058751
  animal model positive animal study
• The Potential of Hydrogen for Improving Mental Disorders.
  2021 ・ Curr Pharm Des ・ PMID 33185151
  not specified not assessed review